Determination of Formation Constant and Thermodynamic Parameters for Interaction between Vanadyl Sulfate and Gliclazide in Aqueous – Organic Solvent at Various Temperatures

Our work aims to measure the conductivity of vanadyl complexes in an aqueous-organic medium at various temperatures ranging from (298.15, 303.15, 308.15 and 313.15 K). The experimental data of Λm and Λo were dissected in place of the calculation of formation constants for every form of the stoichiometric complexes. The formation constants (Kf) for the metal complexes were studied for every form of complexes obtained 1:1 and 1:2 metal to ligand molar ratio (M:L) via using formation equation. It is observed that the limiting equivalent conductance increased with the increment in temperature. Thermodynamic parameters (i.e., ΔG0f, ΔH0f, ΔS0f) are estimated from the temperature dependence of the ion formation constant. Vanadyl complexes show formation within experimentally various temperatures which are supported by the negative value of ΔG0f. The positive values of ΔS0f in most cases and positive values of ΔH0f indicate that the formation process occurred spontaneously as well as endothermic and vice versa at all respective temperatures.