The Effect of Buprenorphine and Bupropion in the Treatment of Methamphetamine Dependency and Craving

Background: Methamphetamine dependency and abuse is a growing problem in the world.

Objective: To compare efficacy of buprenorphine and bupropion in the treatment of methamphetamine craving in a single case.

Results: Buprenorphine is more effective than bupropion in the treatment of methamphetamine craving.

Discussion: This case indicates although both buprenorphine and bupropion could be beneficial in treating methamphetamine dependency and withdrawal craving, however, buprenorphine is much more effective than bupropion.

Conclusion: To our knowledge there is not any report on buprenorphine use in the treatment of methamphetamine craving in Iran and other countries as well, therefore this case-study of an Iranian patient could represent the most innovative information.