Exploring the Complex Relationship between Psychological Stress and Fertility: Implications for Population Growth in Developing Countries

Uncontrolled population growth has raised serious concerns among future policymakers. Although fertility rate has declined substantially over time, in developing countries the rate is still very high. Most of these countries face serious issues such as; severe poverty, malnutrition, unemployment, homelessness, financial insecurity, and medical insufficiency, leading to psychological distress. This article explores the mechanisms of psychological stress and its potential effects on human fertility. An attempt is made to differ from the existing claim that stress is anti-steroidogenic. This counter was based on earlier studies on adaptation of acute stress and overcoming stress stimuli. Which have asserted that individual adaptive abilities can alter the negative outcome of psychological stress depending on genetic, environmental, and behavioural factors. One of such adaptations comes from mitochondrial efficiency. An extensive energy demand during stress is achieved through competitive mitochondrial biogenesis. Earlier studies have noted that psychological stress triggers mitochondrial biogenesis. Thus, theoretically, mitochondrial biogenesis may also contribute in augmenting quality of sperm. In conclusion, stress induced biogenesis of mitochondria may contribute in enhancing fertility. Future studies on the degree of psychological stress and its possible retaliation through mitochondrial biogenesis, and subsequent responses to metabolic, and mechanical pathways, would open new avenues in understanding human fertility.