THE ROLE OF HUMAN PAPILLOMAVIRUS IN DEVELOPMENT OF OROPHARYNGEAL CANCER

Stukan, A. I. and Bodnya, V. N. and Dulina, E. V. and Leonov, A. A. and Aleksandrov, V. I. (2016) THE ROLE OF HUMAN PAPILLOMAVIRUS IN DEVELOPMENT OF OROPHARYNGEAL CANCER. Kuban Scientific Medical Bulletin, 6 (5). pp. 154-157.

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Abstract

This article provides review of foreign literature on the problem of HPV-associated oropharyngeal cancer incidence. Epidemiological researches demonstrate increase of incidence of oropharyngeal squamous cell carcinoma (OPSCC) especially among white men of middle age. Such growth of oropharyngeal cancer incidence is associated with human papilloma virus type 16 (HPV 16). The p16 - protein expression is the marker of HPV DNA integration into human nuclear DNA. It is suggested that detection of tumor HPV-status can predict prognosis and develop preventive measures.

Item Type: Article
Subjects: STM Library Press > Medical Science
Depositing User: Unnamed user with email support@stmlibrarypress.com
Date Deposited: 05 Apr 2023 05:32
Last Modified: 22 Oct 2024 04:10
URI: http://journal.scienceopenlibraries.com/id/eprint/876

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